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Our Story

Our mission is to discover, develop, and commercialize medicines that improve the lives of patients by combining the potential of high-value GPCR drug targets with the power of state-of-the-art small molecule drug discovery technologies. Septerna’s Native Complex™ Platform is the engine that will make this happen, moving ideas for disease-modifying therapies from possibility to reality.

Septerna has assembled a team that thrives on innovation, combining pioneering GPCR scientists with experienced drug hunters. Our founders have made seminal discoveries that reveal the inner workings of GPCRs and how they control physiology. Our scientists have built upon these unique insights to develop our industrial-scale Native Complex™ Platform.

We are focusing the Native Complex™ Platform on tackling previously difficult-to-drug GPCR targets, and our small molecule drug discovery efforts have rapidly advanced, resulting in a pipeline of innovative programs. With an unprecedented level of productivity, we are setting the stage for a new future for GPCR-targeted medicines.

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Our Team

Alan Ezekowitz, MD, DPhil

Interim Chief Medical Officer

Ali Masoudi, PhD

Protein Sciences

Amer M. Mirza, PhD

Vice President, Disease Biology and Translational Sciences

Andres Perez Rivas

Protein Sciences

Ariel Wein, PhD

Protein Sciences

Bartholomew Roland, PhD

Discovery Biology

Cameron Smith, MS

Drug Discovery

Chia-Hung Tai

Discovery Biology

Chris Heise, PhD

Vice President, Discovery Biology

Daniel Long, DPhil

Senior Vice President, Drug Discovery

Dean P. Staus, PhD

Protein Sciences

Elyas Kefela

Operations

George Xu, PhD

Director, Corporate Strategy & Portfolio Development

Ivan Gomez

Disease Biology

Jasleen Sodhi, PhD

DMPK

Jeffrey Finer, MD, PhD

Chief Executive Officer and Co-founder

Jialu Wang, PhD

Protein Sciences

Jun Zhang

Disease Biology

Kathryn Luderman, PhD

Discovery Biology

Ken Eng

Human Resources

Kiana Alvarez

Disease Biology

Kris Dalmacio

Operations

Liz Bhatt, MS, MBA

Chief Operating Officer

Matthew Volgraf, PhD

Medicinal Chemistry

Mel Manalo, MSc, PMP

Technology

Michael Broeker

Operations

Michael Wong

Protein Sciences

Miles Yamasaki

Protein Sciences

Parker Deal, PhD

Discovery Biology

Paul Gibbons

Computational Chemistry

Phillip Schwartz

Discovery Biology

Ran Xiao

Vice President of Finance and Business Operations

Rene Harper

Discovery Biology

Richard Hansen, PhD

Vice President, Technology

Richard van Rijn, PhD

Disease Biology

Robert Keyser

Technology

Ryan Muir, PhD

Discovery Biology

Ryan Strachan, PhD

Discovery Biology

Sigrid Noreng, PhD

Protein Sciences

Steve McKerrall

Medicinal Chemistry

Uwe Klein, PhD

Senior Vice President, Biological Sciences

Victoria Wu, PhD

Disease Biology

Xiang Zhou, PhD

Medicinal Chemistry

Xiaohui Du, PhD

Medicinal Chemistry

Our Teams

Robert Lefkowitz, MD

Duke University, HHMI

Arthur Christopoulos, PhD

Monash University

Patrick Sexton, PhD, DSc

Monash University

Jeffrey Finer, MD, PhD

Chief Executive Officer and Co-founder

Investors

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Real Team. Real Purpose.

Our Story

Our Team

Our Teams

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Real Team.

Real Purpose.