Denise Wootten, PhD
Denise Wootten is a Professor in the Faculty of Pharmacy and Pharmaceutical Sciences at Monash University, a Senior Research Fellow of the National Health and Medical Research Council of Australia, and the Monash node leader for the ARC Centre for Cryo-EM of Membrane Proteins (CCeMMP).
Prof. Wootten is an international expert in the study of GPCRs, particularly the class B1 GPCR subfamily. Her research is focused on understanding GPCR targeting in particular modes of GPCR activation, signalling and regulation, biased agonism, allosteric modulation and the interaction of receptors with regulatory accessory proteins. She has significant expertise in the application of cryo-EM to GPCR structure elucidation, and her research incorporates structural biology (cryo-EM), molecular, cellular and analytical pharmacology, computational biology, and preclinical mouse models of metabolic disease.
Dr. Wootten completed her PhD at the University of Birmingham, UK.